Ara-Neplanocin A analogues are synthesized in the microwave under sub-ambient conditions in minutes rather than hours with goods yields. The CoolMate accessory allows for sub-ambient microwave assisted conditions which increase the reaction rate while minimizing by-product formation.

        在微波的條件下，僅需幾分鐘就可以得到ara-neplanocin類似物幾小時產量。該coolmate配件可在低溫下進行微波輔助反應，提高反應速度的同時zui大限度地減少副產物的生成。